The Surgical Treatment of Prolactinomas

Predictors of Outcome and Long-Term Results

The February, l999 issue of the journal Neurosurgery contains a report by Tyrrell and colleagues from the University of California in San Francisco (UCSF) in which early outcomes and long-term results are analyzed in a large series of patients with prolactinomas following transsphenoidal microsurgery. Two groups of patients treated in different periods of time were followed, and outcomes including complications were evaluated to provide information on the benefits and risks of microsurgery in the management of prolactinomas. The author, J. Blake Tyrrell, is Professor of Medicine and Head of the Section of Endocrinology at UCSF. All patients were operated on by Charles B. Wilson, Professor of Neurosurgery at UCSF. The statistical analysis was performed by Kathleen R. Lamborn, also at UCSF.

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